The patent badge is an abbreviated version of the USPTO patent document. The patent badge does contain a link to the full patent document.
The patent badge is an abbreviated version of the USPTO patent document. The patent badge covers the following: Patent number, Date patent was issued, Date patent was filed, Title of the patent, Applicant, Inventor, Assignee, Attorney firm, Primary examiner, Assistant examiner, CPCs, and Abstract. The patent badge does contain a link to the full patent document (in Adobe Acrobat format, aka pdf). To download or print any patent click here.
Patent No.:
Date of Patent:
Jul. 11, 1989
Filed:
Feb. 08, 1988
Applicant:
Inventors:
James R McCarthy, West Chester, OH (US);
Thomas M Bargar, Clayton, CA (US);
Charlotte L Barney, Cincinnati, OH (US);
Donald P Matthews, West Chester, OH (US);
Robert J Broersma, Noblesville, IN (US);
Assignee:
Merrell Dow Pharmaceuticals Inc., Cincinnati, OH (US);
Attorney:
Primary Examiner:
Assistant Examiner:
Int. Cl.
CPC ...
A61K / ; C07D / ; C07D / ;
U.S. Cl.
CPC ...
514438 ; 514445 ; 514446 ; 514448 ; 549 65 ; 549 72 ; 549 71 ; 549 74 ; 549 64 ;
Abstract
The present invention relates to compounds which are allenyl amines, more specifically, .beta.-ethenylidene-(substituted)ethanamines, possessing antihypertensive activity. They are prepared by a noval reaction of a protected N,N-bis(trimethylsilyl)-4-methoxy-2-butynylamine compound with a metallo-organic compound, with subsequent removal of the silyl protecting groups to provide the desired compound.