The patent badge is an abbreviated version of the USPTO patent document. The patent badge does contain a link to the full patent document.

The patent badge is an abbreviated version of the USPTO patent document. The patent badge covers the following: Patent number, Date patent was issued, Date patent was filed, Title of the patent, Applicant, Inventor, Assignee, Attorney firm, Primary examiner, Assistant examiner, CPCs, and Abstract. The patent badge does contain a link to the full patent document (in Adobe Acrobat format, aka pdf). To download or print any patent click here.

Date of Patent:
Jul. 04, 1989

Filed:

May. 22, 1987
Applicant:
Inventors:

Richard Colonno, New Britain Township, Bucks County, PA (US);

Victor M Garsky, Blue Bell, PA (US);

John Hannah, Matawan, NJ (US);

Robert B Stein, Rydal, PA (US);

Richard L Tolman, Warren, NJ (US);

Assignee:

Merck & Co., Inc., Rahway, NJ (US);

Attorneys:
Primary Examiner:
Assistant Examiner:
Int. Cl.
CPC ...
C07K / ; C12N / ; A61K / ;
U.S. Cl.
CPC ...
530330 ; 530324 ; 530325 ; 530326 ; 530327 ; 530328 ; 530329 ; 514 15 ; 514 17 ; 514 14 ; 514 16 ; 435184 ;
Abstract

The pentapeptide Val Val Asn Asp Leu has been found to be the shortest peptide sequence that inhibits the activity of the ribonucleotide reductase enzyme of herpes simplex virus in vitro thereby inhibiting viral replication. Longer peptides containing the foregoing pentapeptide sequence are more potent inhibitors.


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