The patent badge is an abbreviated version of the USPTO patent document. The patent badge does contain a link to the full patent document.
The patent badge is an abbreviated version of the USPTO patent document. The patent badge covers the following: Patent number, Date patent was issued, Date patent was filed, Title of the patent, Applicant, Inventor, Assignee, Attorney firm, Primary examiner, Assistant examiner, CPCs, and Abstract. The patent badge does contain a link to the full patent document (in Adobe Acrobat format, aka pdf). To download or print any patent click here.
Patent No.:
Date of Patent:
Jul. 04, 1989
Filed:
Nov. 06, 1987
Pawan Seth, Oberwil, CH;
Mepha AG, Aesch, CH;
Abstract
The process results in an adhesive plaster for the transdermal adminstration of pharmaceutical, in particular heat-sensitive, active substances, composed of an adhesive layer, a backing layer, a matrix layer containing the active substances, and a protective layer. The flux of active substance release is controlled by its diffusion from the matrix layer. The latter is produced by the hot melt method, by mixing an ethylene/vinyl acetate copolymer and an involatile, hydrophobic excipient which is miscible with the latter, is compatible with the active substance and is tolerated by the skin, for example isopropyl myristate or a triglyceride, at the melting point of the mixture, and incorporation therein of a solution or dispersion of the active substance in a small amount of the same excipient.