The patent badge is an abbreviated version of the USPTO patent document. The patent badge does contain a link to the full patent document.

The patent badge is an abbreviated version of the USPTO patent document. The patent badge covers the following: Patent number, Date patent was issued, Date patent was filed, Title of the patent, Applicant, Inventor, Assignee, Attorney firm, Primary examiner, Assistant examiner, CPCs, and Abstract. The patent badge does contain a link to the full patent document (in Adobe Acrobat format, aka pdf). To download or print any patent click here.

Date of Patent:
Jun. 20, 1989

Filed:

Jun. 17, 1987
Applicant:
Inventors:

Tameo Iwasaki, Nishinomiya, JP;

Kohki Takashima, Tokyo, JP;

Assignee:
Attorney:
Primary Examiner:
Assistant Examiner:
Int. Cl.
CPC ...
C07C / ; A61K / ; A61K / ;
U.S. Cl.
CPC ...
5142395 ; 514183 ; 5142222 ; 5142288 ; 514277 ; 514359 ; 514408 ; 514430 ; 514438 ; 514449 ; 514463 ; 514466 ; 514468 ; 514533 ; 514534 ; 514544 ; 514510 ; 514824 ; 544-2 ; 544-3 ; 544 59 ; 544 63 ; 544106 ; 546206 ; 546400 ; 549 13 ; 549 14 ; 549 29 ; 549 30 ; 549356 ; 549359 ; 549429 ; 560 51 ; 560 53 ; 560 56 ;
Abstract

Naphthalene derivative of the formula: ##STR1## wherein Ring A is a substituted or unsubstituted benzene ring; each of R.sup.1 and R.sup.2 is a group of the formula: --OR.sup.5, --NHR.sup.5 or ##STR2## or either one of R.sup.1 and R.sup.2 is a lower alkoxy group and the other one is a group of the formula: --OR.sup.5, --NHR.sup.5 or ##STR3## each of R.sup.3 and R.sup.4 is a lower alkoxy group, or one of R.sup.3 and R.sup.4 is a lower alkoxy group and the other is a hydrogen atom; R.sup.5 is a substituted alkyl group, a heterocyclic group, a cycloalkyl group, an alkyl group of at least 5 carbon atoms or alkenyl group; and each of R.sup.6 and R.sup.7 is hydrogen atom or a lower alkyl group and salts thereof are disclosed. Said naphthalene derivative (I) and its salts have excellent hypolipidemic activity and are useful for treatment or prophylaxis of hyperlipidemia and/or arteriosclerosis.


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