The patent badge is an abbreviated version of the USPTO patent document. The patent badge does contain a link to the full patent document.
The patent badge is an abbreviated version of the USPTO patent document. The patent badge covers the following: Patent number, Date patent was issued, Date patent was filed, Title of the patent, Applicant, Inventor, Assignee, Attorney firm, Primary examiner, Assistant examiner, CPCs, and Abstract. The patent badge does contain a link to the full patent document (in Adobe Acrobat format, aka pdf). To download or print any patent click here.
Patent No.:
Date of Patent:
Jun. 06, 1989
Filed:
Sep. 10, 1986
Applicant:
Inventors:
Fumio Kakimoto, Gifu, JP;
Naoki Asakawa, Gifu, JP;
Yasuo Ishibashi, Gifu, JP;
Yasuo Miyake, Aichi, JP;
Assignee:
Eisai Co., Ltd., Tokyo, JP;
Attorney:
Primary Examiner:
Assistant Examiner:
Int. Cl.
CPC ...
A61R / ;
U.S. Cl.
CPC ...
424 943 ; 424 941 ; 424 9464 ; 435212 ; 435215 ; 435217 ; 435188 ; 514 21 ; 514970 ; 530354 ;
Abstract
A composition containing a tissue Plasminogen Activator (tPA) which comprises a partial hydrolyzate of gelatin cross-linked to a diisocyanate as an essential ingredient; or alternatively a partial hydrolyzate of gelatin cross-linked to a diisocyanate and one or more of a basic amino acid or salt thereof. The composition enhances the solubility of the tPA in water, thereby making the tPA further available in the treatment of circulatory diseases caused by thrombi.