The patent badge is an abbreviated version of the USPTO patent document. The patent badge does contain a link to the full patent document.
The patent badge is an abbreviated version of the USPTO patent document. The patent badge covers the following: Patent number, Date patent was issued, Date patent was filed, Title of the patent, Applicant, Inventor, Assignee, Attorney firm, Primary examiner, Assistant examiner, CPCs, and Abstract. The patent badge does contain a link to the full patent document (in Adobe Acrobat format, aka pdf). To download or print any patent click here.
Patent No.:
Date of Patent:
May. 30, 1989
Filed:
Mar. 20, 1987
Applicant:
Inventor:
Charles B Shoemaker, Belmont, MA (US);
Assignee:
Genetics Institute, Inc., Cambridge, MA (US);
Primary Examiner:
Assistant Examiner:
Int. Cl.
CPC ...
C07K / ; C12N / ; C12N / ; C12P / ;
U.S. Cl.
CPC ...
530397 ; 530350 ; 530380 ; 530399 ; 530395 ; 530829 ; 530830 ; 435 68 ; 4351723 ; 4352402 ; 514-8 ; 514 21 ; 514814 ; 935 13 ; 935 19 ; 935 70 ; 536 27 ; 536 28 ; 536 29 ;
Abstract
A new improved glycoprotein having erythropoietin-type activity is disclosed. The substrate is characterized by amino acid sequence substantially identical to the amino acid sequence of native human erythropoietin wherein the methionine-54 is replaced with leucine. DNA encoding for the EPO-substance and expression vectors incorporating the same are disclosed. Therapeutic compositions and methods for treatment of anemic conditions are described.