The patent badge is an abbreviated version of the USPTO patent document. The patent badge does contain a link to the full patent document.
The patent badge is an abbreviated version of the USPTO patent document. The patent badge covers the following: Patent number, Date patent was issued, Date patent was filed, Title of the patent, Applicant, Inventor, Assignee, Attorney firm, Primary examiner, Assistant examiner, CPCs, and Abstract. The patent badge does contain a link to the full patent document (in Adobe Acrobat format, aka pdf). To download or print any patent click here.
Patent No.:
Date of Patent:
May. 30, 1989
Filed:
May. 15, 1985
Applicant:
Inventors:
Anthony W Siadak, Seattle, WA (US);
Mark E Lostrom, Redmond, WA (US);
Assignees:
Genetics Corporation, Seattle, WA (US);
Miles, Inc., Elkhart, IN (US);
Attorney:
Primary Examiner:
Int. Cl.
CPC ...
A61K / ; C07K / ; C12N / ;
U.S. Cl.
CPC ...
424 87 ; 530387 ; 530388 ; 435-7 ; 435 68 ; 435 70 ; 4351722 ; 4351723 ; 4352402 ; 435948 ; 935100 ; 935107 ; 935 52 ; 935 71 ; 436548 ;
Abstract
Transformed human lymphocyte cell lines have been produced which secrete human monoclonal antibodies to serotypic determinants on LPS molecules of gram-negative bacteria. These antibodies have been found to be protective against lethal challenges of the homologous bacteria. Pharmaceutical compositions containing these antibodies and their prophylactic and therapeutic use in the management of gram-negative disease in humans are also disclosed.