The patent badge is an abbreviated version of the USPTO patent document. The patent badge does contain a link to the full patent document.

The patent badge is an abbreviated version of the USPTO patent document. The patent badge covers the following: Patent number, Date patent was issued, Date patent was filed, Title of the patent, Applicant, Inventor, Assignee, Attorney firm, Primary examiner, Assistant examiner, CPCs, and Abstract. The patent badge does contain a link to the full patent document (in Adobe Acrobat format, aka pdf). To download or print any patent click here.

Date of Patent:
May. 23, 1989

Filed:

May. 26, 1987
Applicant:
Inventor:

Vinit Saxena, Pinole, CA (US);

Assignee:

Sepragen Corporation, San Leandro, CA (US);

Attorney:
Primary Examiner:
Assistant Examiner:
Int. Cl.
CPC ...
C12N / ; C12M / ; C12M / ;
U.S. Cl.
CPC ...
43524024 ; 43524023 ; 435288 ; 435284 ; 210617 ; 210618 ;
Abstract

A bioreactor for anchorage or nonanchorage dependent cells or for immobilized enzymes that is capable of achieving high cell densities or concentrations of reaction products is disclosed. The bioreactor is capable of being easily scaled up. The bioreactor utilizes horizontal or radial flow of the culture or growth medium across a packed bed of microcarriers with attached cells or enzymes. The radial flow utilized by the chamber minimizes the non-optimal culture perfusion problems and maximizes the uniformity of medium delivery and cell and/or enzyme viability. The cell culture chamber possess the capability for the production of many industrially important and useful products, particularly in the medical, pharmaceutical, food, agricultural, environmental and purification industries. In the medical and pharmaceutical industries, the large scale production of therapeutically important substances such as anti-tumor factors, hormones, viral antigens, enzymes, interferons and other valuable biomolecules, is greatly facilitated.


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