The patent badge is an abbreviated version of the USPTO patent document. The patent badge does contain a link to the full patent document.

The patent badge is an abbreviated version of the USPTO patent document. The patent badge covers the following: Patent number, Date patent was issued, Date patent was filed, Title of the patent, Applicant, Inventor, Assignee, Attorney firm, Primary examiner, Assistant examiner, CPCs, and Abstract. The patent badge does contain a link to the full patent document (in Adobe Acrobat format, aka pdf). To download or print any patent click here.

Date of Patent:
May. 16, 1989

Filed:

Jul. 03, 1986
Applicant:
Inventors:

Wolfgang von der Saal, Weinheim, DE;

Alfred Mertens, Schriesheim, DE;

Herbert Berger, Mannheim, DE;

Bernd Muller-Beckmann, Grunstadt, DE;

Klaus Strein, Hemsbach, DE;

Assignee:

Boehringer Mannheim GmbH, Mannheim, DE;

Attorney:
Primary Examiner:
Int. Cl.
CPC ...
A61K / ; C07D / ; C07D / ;
U.S. Cl.
CPC ...
514254 ; 514183 ; 514212 ; 5142268 ; 5142272 ; 5142285 ; 5142288 ; 5142328 ; 514241 ; 514245 ; 514253 ; 514256 ; 514322 ; 514338 ; 514359 ; 514361 ; 514362 ; 514363 ; 514364 ; 514365 ; 514366 ; 514369 ; 514370 ; 514372 ; 514374 ; 514375 ; 514376 ; 514377 ; 514378 ; 514380 ; 514381 ; 514382 ; 514383 ; 514384 ; 514387 ; 514388 ; 514394 ; 514395 ; 540603 ; 544 54 ; 544 55 ; 544 585 ; 544 587 ; 544 96 ; 544 98 ; 544135 ; 544137 ; 544139 ; 544179 ; 544180 ; 544212 ; 544238 ; 544319 ; 544328 ; 544333 ; 544405 ; 546199 ; 546271 ; 548127 ; 548128 ; 548129 ; 548130 ; 548131 ; 548132 ; 548133 ; 548134 ; 548135 ; 548137 ; 548138 ; 548141 ; 548142 ; 548143 ; 548144 ; 548151 ; 548181 ; 548213 ; 548214 ; 548218 ; 548225 ; 548233 ; 548235 ; 548236 ; 548243 ; 548245 ; 548247 ; 548248 ; 548251 ; 548254 ; 548255 ; 548263 ; 548264 ; 548266 ; 548267 ; 548269 ; 548305 ; 548306 ; 548326 ;
Abstract

The present invention provides benzimidazoles of the general formula: ##STR1## wherein R.sub.1, X, A, and R.sub.2 are as defined in the specification. The present invention also provides processes for the preparation of these new benzimidazoles and pharmaceutical compositions containing them, as well as intermediates for the preparation thereof. The new benzimidazoles are useful to treat heart or circulatory diseases which respond to a lowering of blood pressure, a positive inotropic action and/or an improvement in microcirculation.


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