The patent badge is an abbreviated version of the USPTO patent document. The patent badge does contain a link to the full patent document.
The patent badge is an abbreviated version of the USPTO patent document. The patent badge covers the following: Patent number, Date patent was issued, Date patent was filed, Title of the patent, Applicant, Inventor, Assignee, Attorney firm, Primary examiner, Assistant examiner, CPCs, and Abstract. The patent badge does contain a link to the full patent document (in Adobe Acrobat format, aka pdf). To download or print any patent click here.
Patent No.:
Date of Patent:
May. 09, 1989
Filed:
Sep. 16, 1987
Geza Szilagyi, Budapest, HU;
Eva Bozo, Budapest, HU;
Laszlo Czollner, Budapest, HU;
Laszlo Jaszlits, Budapest, HU;
Gyorgy Rabloczky, Budapest, HU;
Jozsef Borsi, Budapest, HU;
Istvan Elekes, Budapest, HU;
Gyongyi Nagy nee Csokas, Budapest, HU;
Andras Varro, Budapest, HU;
ZSuzanne Lang nee Rihmer, Budapest, HU;
Gyorgy Cseh, Budapest, HU;
Gyula Horvath, Budapest, HU;
Ilona Bodi, Eger, HU;
Alkaloida Vegyeszeti Gyar, Tiszavasvari, HU;
Abstract
The invention relates to new substituted dihydropyridine derivatives of the general formula (I), ##STR1## wherein R.sup.1 and R.sup.6 are as defined herein after, the racemic and optically active variants as well as mixtures thereof, furthermore the acid addition salts of these compounds, pharmaceutical compositions containing the same and a process for the preparation thereof. The compounds of the general formula (I) can be advantageously applied for the treatment of pathologically severe hypertensions, their toxicity is low and they possess an advantageous therapeutic index.