The patent badge is an abbreviated version of the USPTO patent document. The patent badge does contain a link to the full patent document.
The patent badge is an abbreviated version of the USPTO patent document. The patent badge covers the following: Patent number, Date patent was issued, Date patent was filed, Title of the patent, Applicant, Inventor, Assignee, Attorney firm, Primary examiner, Assistant examiner, CPCs, and Abstract. The patent badge does contain a link to the full patent document (in Adobe Acrobat format, aka pdf). To download or print any patent click here.
Patent No.:
Date of Patent:
Apr. 18, 1989
Filed:
Dec. 11, 1987
Applicant:
Inventors:
Assignee:
Sankyo Company Limited, Tokyo, JP;
Attorney:
Primary Examiner:
Int. Cl.
CPC ...
C07D / ; C07H / ;
U.S. Cl.
CPC ...
544277 ; 435119 ; 536 22 ; 536 26 ;
Abstract
Dihydrodesoxygriseolic acid, which has the formula ##STR1## and salts and esters thereof may be prepared by cultivating a suitable strain of Streptomyces, e.g. Streptomyces griseoaurantiacus No. 43894, and, if necessary, salifying or esterifying the free acid. These compounds inhibit the activity of various cyclic nucleotide phosphodiesterases, particularly cAMP PDE, and, as a result of this, have a variety of physiological activities and uses.