The patent badge is an abbreviated version of the USPTO patent document. The patent badge does contain a link to the full patent document.
The patent badge is an abbreviated version of the USPTO patent document. The patent badge covers the following: Patent number, Date patent was issued, Date patent was filed, Title of the patent, Applicant, Inventor, Assignee, Attorney firm, Primary examiner, Assistant examiner, CPCs, and Abstract. The patent badge does contain a link to the full patent document (in Adobe Acrobat format, aka pdf). To download or print any patent click here.
Patent No.:
Date of Patent:
Apr. 18, 1989
Filed:
May. 18, 1987
Applicant:
Inventor:
Arnold L Newman, Kensington, MD (US);
Assignee:
The Johns Hopkins University, Baltimore, MD (US);
Attorneys:
Primary Examiner:
Int. Cl.
CPC ...
G01N / ;
U.S. Cl.
CPC ...
422 68 ; 324 / ; 422 69 ; 422 90 ; 422 98 ; 435817 ; 436528 ; 436806 ;
Abstract
An apparatus for detecting the presence and/or measuring the concentration of an analyte in the fluid medium is disclosed. The apparatus relies on biospecific binding between a biochemical binding system and the analyte to change the dielectric properties of a capacitive affinity sensor. The biological affinity sensor is optimized by: (1) adjusting the thickness and dielectric properties of a passivation layer to generally match the impedance of the biological binding system; and (2) minimize the double layer capacitance so that bulk capacitance changes associated with the biological binding system are maximized.