The patent badge is an abbreviated version of the USPTO patent document. The patent badge does contain a link to the full patent document.

The patent badge is an abbreviated version of the USPTO patent document. The patent badge covers the following: Patent number, Date patent was issued, Date patent was filed, Title of the patent, Applicant, Inventor, Assignee, Attorney firm, Primary examiner, Assistant examiner, CPCs, and Abstract. The patent badge does contain a link to the full patent document (in Adobe Acrobat format, aka pdf). To download or print any patent click here.

Date of Patent:
Apr. 11, 1989

Filed:

Jul. 11, 1988
Applicant:
Inventors:

Setsurou Fujii, Kyoto, JP;

Toshiyuki Okutome, Tokyo, JP;

Toyoo Nakayama, Funabashi, JP;

Shigeki Nunomura, Chiba, JP;

Kimio Sudo, Chiba, JP;

Shinichi Watanabe, Otsu, JP;

Masateru Kurumi, Narita, JP;

Takuo Aoyama, Sakura, JP;

Assignee:

Torii & Co., Ltd., Tokyo, JP;

Attorney:
Primary Examiner:
Int. Cl.
CPC ...
A61K / ; C07C / ;
U.S. Cl.
CPC ...
514510 ; 560 34 ;
Abstract

Amidine compounds of formula (I) ##STR1## and the pharmaceutically acceptable acid addition salts thereof are novel and are of use as anti-trypsin, anti-plasmin, anti-kallikrein, anti-thrombin and anti-complement agents which may be administered orally. These amidine compounds can be produced by the reaction between a carboxylic acid compound of formula (II) ##STR2## or a reactive intermediate thereof and 6-amidino-2-naphthol of formula (III) ##STR3## or preferably an acid addition salt thereof.


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