The patent badge is an abbreviated version of the USPTO patent document. The patent badge does contain a link to the full patent document.

The patent badge is an abbreviated version of the USPTO patent document. The patent badge covers the following: Patent number, Date patent was issued, Date patent was filed, Title of the patent, Applicant, Inventor, Assignee, Attorney firm, Primary examiner, Assistant examiner, CPCs, and Abstract. The patent badge does contain a link to the full patent document (in Adobe Acrobat format, aka pdf). To download or print any patent click here.

Date of Patent:
Mar. 28, 1989

Filed:

Feb. 18, 1986
Applicant:
Inventors:

Nicole Suciu-Foca, Cliffside Park, NJ (US);

Donald W King, Chicago, IL (US);

Attorney:
Primary Examiner:
Int. Cl.
CPC ...
C12N / ; C07K / ;
U.S. Cl.
CPC ...
43524027 ; 530387 ; 424 858 ; 435 68 ; 4351722 ; 935104 ; 935110 ;
Abstract

Late differentiation antigens (LDA.sub.1 and LDA.sub.2) expressed by activated helper cells are described. LDA.sub.1 and LDA.sub.2 are membrane proteins recognized by monoclonal antibodies produced by immunizing mice with alloreactive human T cell clones with helper function. LDA.sub.1 and LDA.sub.2 are expressed by helper T cells. LDA.sub.1 monoclonal antibody and LDA.sub.2 monoclonal antibody block T cell enhancement of B cell immunoglobulin production. Thus, LDA.sub.1 and LDA.sub.2 are associated with helper T cell effector function. Methods of diagnosis and therepy based upon LDA.sub.1 and LDA.sub.2 are also described.


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Suciu-Foca, Nicole. (1989). Late differentiation antigens associated with helper t lymphocyte (U.S. Patent No. 4816404). U.S. Patent and Trademark Office. https://idiyas.com/patent/badge/4816404

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