The patent badge is an abbreviated version of the USPTO patent document. The patent badge does contain a link to the full patent document.

The patent badge is an abbreviated version of the USPTO patent document. The patent badge covers the following: Patent number, Date patent was issued, Date patent was filed, Title of the patent, Applicant, Inventor, Assignee, Attorney firm, Primary examiner, Assistant examiner, CPCs, and Abstract. The patent badge does contain a link to the full patent document (in Adobe Acrobat format, aka pdf). To download or print any patent click here.

Date of Patent:
Mar. 21, 1989

Filed:

Sep. 28, 1987
Applicant:
Inventors:

Iren Barta, Budapest, HU;

Pal Fekete, Budapest, HU;

Laszlo Pallos, Budapest, HU;

Gabor Kovacs, Budapest, HU;

Lajos Mahr, Budapest, HU;

Assignees:

Egis Gyogyszergyar, Budapest, HU;

Muanyagipari Kutato Intezet, Budapest, HU;

Attorneys:
Primary Examiner:
Assistant Examiner:
Int. Cl.
CPC ...
A61F / ;
U.S. Cl.
CPC ...
424448 ; 424449 ; 427171 ;
Abstract

The invention relates to a transdermal laminated pharmaceutical composition (plaster) having prolonged effect, wherein one or more storing layer(s) comprising the active ingredient, an ethylene/vinyl acetate copolymer regulating layer and an adhesive layer are applied onto the carrier. The pharmaceutical composition is prepared by coupling a carrier comprising the active ingredient with a regulating layer consisting of an ethylene/vinyl acetate copolymer foil having a vinal acetate content of 2-40 molar %. The foil is previously irradiated in a thickness of 100-300 .mu.m with a high-energy irradiation in a dose of 1-15 Mrad--preferably with electrone radiation--and thereafter stretched at 80.degree.-90.degree. C. to a thickness of 2-200 .mu.m. The system comprising the carrier and the regulating layer is subsequently coupled with an adhesive layer.


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