The patent badge is an abbreviated version of the USPTO patent document. The patent badge does contain a link to the full patent document.

The patent badge is an abbreviated version of the USPTO patent document. The patent badge covers the following: Patent number, Date patent was issued, Date patent was filed, Title of the patent, Applicant, Inventor, Assignee, Attorney firm, Primary examiner, Assistant examiner, CPCs, and Abstract. The patent badge does contain a link to the full patent document (in Adobe Acrobat format, aka pdf). To download or print any patent click here.

Date of Patent:
Feb. 14, 1989

Filed:

Aug. 19, 1987
Applicant:
Inventors:

Ray F Cracauer, Minneapolis, MN (US);

Robert D Walker, Ham Lake, MN (US);

Micheal L Gruenberg, Coon Rapids, MN (US);

Assignee:

Endotronics, Inc., Coon Rapids, MN (US);

Attorney:
Primary Examiner:
Int. Cl.
CPC ...
C12N / ; C12M / ; C12M / ; C02F / ;
U.S. Cl.
CPC ...
435240242 ; 435285 ; 435310 ; 2103232 ; 2103218 ; 21050023 ;
Abstract

An improved cell culturing device includes a hollow fiber cartridge having a shell and a plurality of capillaries extending through the shell with at least some of the capillaries having selectively permeable walls. A cell culturing space is located between the shell and capillaries. The improvement includes a chamber containing a second medium supply fluidly connected to the cell culturing space. A pressurizing system pressurizes the medium within the chamber to a level higher than the level of medium flowing through the lumen of the capillaries. A valving mechanism alternatively and selectively restricts flow of medium between the chamber and the cell culturing space through first and second conduits such that circulation is effected in the cell culturing space.


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