The patent badge is an abbreviated version of the USPTO patent document. The patent badge does contain a link to the full patent document.
The patent badge is an abbreviated version of the USPTO patent document. The patent badge covers the following: Patent number, Date patent was issued, Date patent was filed, Title of the patent, Applicant, Inventor, Assignee, Attorney firm, Primary examiner, Assistant examiner, CPCs, and Abstract. The patent badge does contain a link to the full patent document (in Adobe Acrobat format, aka pdf). To download or print any patent click here.
Patent No.:
Date of Patent:
Feb. 07, 1989
Filed:
Apr. 22, 1987
Applicant:
Inventors:
Ronald A Hitzeman, Pacifica, CA (US);
Arthur D Levinson, Burlingame, CA (US);
Daniel G Yansura, San Francisco, CA (US);
Assignee:
Genentech, Inc., South San Francisco, CA (US);
Attorney:
Primary Examiner:
Int. Cl.
CPC ...
C12P / ; C12P / ; C12P / ; C12N / ;
U.S. Cl.
CPC ...
435 68 ; 435 70 ; 435 71 ; 4351721 ; 4351723 ; 435255 ; 435256 ; 435320 ; 536 27 ; 935 12 ; 935 37 ; 935 61 ; 935 69 ;
Abstract
Hepatitis surface antigen is synthesized in recombinant yeast hosts transformed with vectors encoding hepatitis surface antigen, preferably under the control of the yeast PGK promoter and preferably in the absence of DNA encoding the surface antigen precursor. Hepatitis surface antigen is assembled by yeast into antigenic 22 nm particles even though hepatitis surface antigen bacterial transformants were not known to be capable of assembling the surface antigen into 22 nm particles.