The patent badge is an abbreviated version of the USPTO patent document. The patent badge does contain a link to the full patent document.

The patent badge is an abbreviated version of the USPTO patent document. The patent badge covers the following: Patent number, Date patent was issued, Date patent was filed, Title of the patent, Applicant, Inventor, Assignee, Attorney firm, Primary examiner, Assistant examiner, CPCs, and Abstract. The patent badge does contain a link to the full patent document (in Adobe Acrobat format, aka pdf). To download or print any patent click here.

Date of Patent:
Jan. 31, 1989

Filed:

Jun. 04, 1984
Applicant:
Inventors:

Michel Monsigny, Saint-Cyr-en-Val, FR;

Annie-Claude Roche, Saint-Pryve, FR;

Attorney:
Primary Examiner:
Int. Cl.
CPC ...
C07K / ; C07K / ; A61K / ; A61K / ;
U.S. Cl.
CPC ...
514-8 ; 424 858 ; 424 88 ; 424 89 ; 530322 ; 530395 ; 530397 ;
Abstract

Macromolecular conjugates of muramylpeptides useful as a stimulant of the cellular immune systems have the formula (R--X).sub.m --(LAM) wherein R is an N-acetylmuramylpeptidyl group or a derivative thereof; (LAM) is a neoglycoprotein having affinity for macrophages or monocytes, consisting of a protein covalently substituted by more than five glycidic chains, each having at least five osidic units, X is a covalent bond between a functional group of the peptidic part of R and a functional group of (LAM) or X is the residue of a conventional bifunctional coupling agent capable of bonding to R and (LAM) by formation of covalent bonds; and m is a number greater than or equal to 1.


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