The patent badge is an abbreviated version of the USPTO patent document. The patent badge does contain a link to the full patent document.

The patent badge is an abbreviated version of the USPTO patent document. The patent badge covers the following: Patent number, Date patent was issued, Date patent was filed, Title of the patent, Applicant, Inventor, Assignee, Attorney firm, Primary examiner, Assistant examiner, CPCs, and Abstract. The patent badge does contain a link to the full patent document (in Adobe Acrobat format, aka pdf). To download or print any patent click here.

Date of Patent:
Jan. 17, 1989

Filed:

Sep. 21, 1987
Applicant:
Inventors:

David A Cherry, Ambler, PA (US);

Cynthia A Maryanoff, Solebury Township, PA (US);

John E Mills, Hatfield, PA (US);

Roy A Olofson, State College, PA (US);

James D Rodgers, North Wales, PA (US);

Assignee:

McNeilab, Inc., Springhouse, PA (US);

Attorney:
Primary Examiner:
Assistant Examiner:
Int. Cl.
CPC ...
C07D / ; C07D / ; C07C / ; C07C / ;
U.S. Cl.
CPC ...
544215 ; 544180 ; 544182 ; 544194 ; 544197 ; 544198 ; 544208 ; 544209 ; 544211 ; 544212 ; 544224 ; 544240 ; 544239 ; 544238 ; 544296 ; 544299 ; 544300 ; 544301 ; 544302 ; 544309 ; 544310 ; 544311 ; 544312 ; 544314 ; 544315 ; 544316 ; 544317 ; 544318 ; 544319 ; 544321 ; 544322 ; 544323 ; 544324 ; 544325 ; 544326 ; 544328 ; 544329 ; 544330 ; 544331 ; 544332 ; 544333 ; 544335 ; 544336 ; 544357 ; 544405 ; 544406 ; 546261 ; 546262 ; 546263 ; 546264 ; 546265 ; 546267 ; 546275 ; 546276 ; 546277 ; 546278 ; 546279 ; 546280 ; 546281 ; 546283 ; 546284 ; 546286 ; 546287 ; 546288 ; 546289 ; 546291 ; 546292 ; 546296 ; 546297 ; 546298 ; 546300 ; 546301 ; 546304 ; 546307 ; 546308 ; 546309 ; 546310 ; 546312 ; 546329 ; 546330 ; 546334 ; 546335 ; 546337 ; 546342 ; 548127 ; 548128 ; 548182 ; 548183 ; 548184 ; 548185 ; 548187 ; 548188 ; 548190 ; 548191 ; 548194 ; 548225 ; 548226 ; 548227 ; 548228 ; 548229 ; 548230 ; 548232 ; 548233 ; 548235 ; 548236 ; 548243 ; 548244 ; 548245 ; 548246 ; 548247 ; 548248 ; 548255 ; 548262 ; 548263 ; 548264 ; 548265 ; 548266 ; 548267 ; 548268 ; 548341 ; 548342 ; 548343 ; 548336 ; 548337 ; 548374 ; 548375 ; 548376 ; 548377 ; 548378 ; 548518 ; 548519 ; 548520 ; 548522 ; 548527 ; 548531 ; 548532 ; 548540 ; 548541 ; 548543 ; 548544 ; 548545 ; 548546 ; 548547 ; 548551 ; 548556 ; 548557 ; 548558 ; 548560 ; 548562 ; 560108 ; 560138 ; 568325 ;
Abstract

A method for the synthesis of the 2-propanone (I) is described starting from alkoxide (II) through the lactone (IV). ##STR1## Excellent control of the location of the substitution on the phenyl ring is achieved and the reaction proceeds in high yield.


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