The patent badge is an abbreviated version of the USPTO patent document. The patent badge does contain a link to the full patent document.
The patent badge is an abbreviated version of the USPTO patent document. The patent badge covers the following: Patent number, Date patent was issued, Date patent was filed, Title of the patent, Applicant, Inventor, Assignee, Attorney firm, Primary examiner, Assistant examiner, CPCs, and Abstract. The patent badge does contain a link to the full patent document (in Adobe Acrobat format, aka pdf). To download or print any patent click here.
Patent No.:
Date of Patent:
Jan. 03, 1989
Filed:
Aug. 27, 1986
Applicant:
Inventors:
Stefan R Woroniecki, Betchworth, GB;
Stephen W Elson, Betchworth, GB;
Keith H Baggaley, Betchworth, GB;
Assignee:
Beecham Group plc, Middlesex, GB;
Primary Examiner:
Int. Cl.
CPC ...
C07D / ; C07D / ; C12P / ; C12P / ;
U.S. Cl.
CPC ...
540348 ; 435119 ; 540362 ;
Abstract
A compound having the formula (I): ##STR1## is described, together with salts thereof and an enzymatic process for converting such compounds into clavulanic acid. A process for the preparation of the compound of formula (I) and its salts is disclosed, together with intermediates for use therein. This process involves the use of a novel enzyme system to effect the desired cyclization, which enzyme system is preferably derived from a micro-organism, in particular a species of Streptomyces.