The patent badge is an abbreviated version of the USPTO patent document. The patent badge does contain a link to the full patent document.

The patent badge is an abbreviated version of the USPTO patent document. The patent badge covers the following: Patent number, Date patent was issued, Date patent was filed, Title of the patent, Applicant, Inventor, Assignee, Attorney firm, Primary examiner, Assistant examiner, CPCs, and Abstract. The patent badge does contain a link to the full patent document (in Adobe Acrobat format, aka pdf). To download or print any patent click here.

Date of Patent:
Jan. 03, 1989

Filed:

May. 29, 1987
Applicant:
Inventors:

Jeffrey D Lifson, Menlo Park, CA (US);

Michael S McGrath, Burlingame, CA (US);

Hin-Wing Yeung, Kowloon, HK;

Kou M Hwang, Danville, CA (US);

Assignees:

Gene Labs, Inc., Redwood City, CA (US);

Regents of University of California, Berkeley, CA (US);

Attorney:
Primary Examiner:
Assistant Examiner:
Int. Cl.
CPC ...
A61K / ; A61K / ; A61K / ; C07G / ;
U.S. Cl.
CPC ...
514-8 ; 514 12 ; 514885 ; 530370 ; 4241951 ;
Abstract

A method of inhibiting expression of HIV antigens in human blood cells infected with HIV. The infected cells are exposed to a plant protein or glycoprotein, such as trichosanthin or momorcharin, at a concentration sufficient to (a) produce a substantial reduction in the level of HIV antigen, and (b) effect a selective reduction in the number of HIV-infected cells, with respect to uninfected cells of the same type. The method is used to treat HIV infection in humans. In another aspect, the invention includes a method of screening drug agents effective in treating HIV infection in humans.


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