The patent badge is an abbreviated version of the USPTO patent document. The patent badge does contain a link to the full patent document.
The patent badge is an abbreviated version of the USPTO patent document. The patent badge covers the following: Patent number, Date patent was issued, Date patent was filed, Title of the patent, Applicant, Inventor, Assignee, Attorney firm, Primary examiner, Assistant examiner, CPCs, and Abstract. The patent badge does contain a link to the full patent document (in Adobe Acrobat format, aka pdf). To download or print any patent click here.
Patent No.:
Date of Patent:
Dec. 13, 1988
Filed:
May. 12, 1987
Applicant:
Inventors:
Tokuyuki Kuroda, Shizuoka, JP;
Koji Hisamura, Mie, JP;
Tohru Sugaya, Shizuoka, JP;
Yutaka Ohsawa, Shizuoka, JP;
Hideo Ueno, Shizuoka, JP;
Makoto Morimoto, Shizuoka, JP;
Tadashi Ashizawa, Shizuoka, JP;
Assignee:
Attorney:
Primary Examiner:
Assistant Examiner:
Int. Cl.
CPC ...
A61K / ; A61K / ; C07D / ;
U.S. Cl.
CPC ...
514256 ; 514370 ; 514377 ; 514383 ; 514397 ; 514402 ; 514410 ; 544322 ; 544328 ; 544331 ; 548181 ; 548233 ; 548255 ; 548266 ; 548336 ; 548348 ; 548422 ;
Abstract
Mitomycin derivatives having potent antitumor activity having the formula: ##STR1## wherein A is ON--or R.sub.4 N.dbd.N--[wherein R.sub.4 is selected from ##STR2## and optionally substituted heterocyclic groups (wherein R.sub.5 and R.sub.8 are each independently selected from hydrogen, lower alkyl and lower cycloalkyl; R.sub.6 is selected from hydrogen, halogen, hydroxy, lower alkoxy, amino and nitro; R.sub.7 is selected from lower alkyl and lower cycloalkyl; and X is selected from oxygen, sulphur and imino)];