The patent badge is an abbreviated version of the USPTO patent document. The patent badge does contain a link to the full patent document.
The patent badge is an abbreviated version of the USPTO patent document. The patent badge covers the following: Patent number, Date patent was issued, Date patent was filed, Title of the patent, Applicant, Inventor, Assignee, Attorney firm, Primary examiner, Assistant examiner, CPCs, and Abstract. The patent badge does contain a link to the full patent document (in Adobe Acrobat format, aka pdf). To download or print any patent click here.
Patent No.:
Date of Patent:
Nov. 29, 1988
Filed:
Nov. 13, 1987
Applicant:
Inventors:
Aldo A Algieri, Fayetteville, NY (US);
Ronnie R Crenshaw, Dewitt, NY (US);
Assignee:
Bristol-Myers Company, New York, NY (US);
Attorney:
Primary Examiner:
Int. Cl.
CPC ...
A61K / ; A61K / ; C07D / ; C07D / ;
U.S. Cl.
CPC ...
514183 ; 514216 ; 514222 ; 514230 ; 514252 ; 514253 ; 514318 ; 514321 ; 514326 ; 514333 ; 514336 ; 514338 ; 514343 ; 514422 ; 514427 ; 514438 ; 514444 ; 514445 ; 540480 ; 540582 ; 540596 ; 540597 ; 544 586 ; 544 587 ; 544131 ; 544146 ; 544360 ; 544364 ; 544377 ; 544379 ; 546194 ; 546197 ; 546213 ; 546256 ; 546270 ; 546281 ; 546284 ; 548526 ; 548527 ; 549 65 ; 549 77 ;
Abstract
Compounds of the formula ##STR1## wherein R.sup.12 is a leaving group, Z is S, O or CH.sub.2 and A is a phenyl, furyl, thienyl or pyridyl ring substituted by a ##STR2## moiety, in which R.sup.8 and R.sup.9 are various substituents or, when taken together with the nitrogen, may be a specified heterocyclic ring, are intermediates in the preparation of histamine H.sub.2 -antagonist anti-ulcer agents of the formula ##STR3## in which R.sup.1 and R.sup.2 are any of several specified substituents.