The patent badge is an abbreviated version of the USPTO patent document. The patent badge does contain a link to the full patent document.
The patent badge is an abbreviated version of the USPTO patent document. The patent badge covers the following: Patent number, Date patent was issued, Date patent was filed, Title of the patent, Applicant, Inventor, Assignee, Attorney firm, Primary examiner, Assistant examiner, CPCs, and Abstract. The patent badge does contain a link to the full patent document (in Adobe Acrobat format, aka pdf). To download or print any patent click here.
Patent No.:
Date of Patent:
Nov. 01, 1988
Filed:
Nov. 24, 1986
Applicant:
Inventors:
Cynthia A Maryanoff, Solebury Township, Bucks County, PA (US);
James N Plampin, Roslyn, PA (US);
Robin C Stanzione, Wayne, PA (US);
Assignee:
McNeilab, Inc., Spring House, PA (US);
Attorney:
Primary Examiner:
Int. Cl.
CPC ...
C07C / ; C07D / ;
U.S. Cl.
CPC ...
260506 ; 544141 ; 546145 ; 546322 ; 548351 ; 549439 ; 558413 ; 560142 ; 540483 ; 260349 ;
Abstract
An efficient synthesis of quanidines, e.g. of the formula (III), by oxidizing a thiourea, e.g. of the following formula (II): ##STR1## with H.sub.2 O.sub.2 and a molybdenum catalyst to yield an aminoiminomethane sulfonic acid which can then be reacted with an amine followed by optional transamination steps.