The patent badge is an abbreviated version of the USPTO patent document. The patent badge does contain a link to the full patent document.

The patent badge is an abbreviated version of the USPTO patent document. The patent badge covers the following: Patent number, Date patent was issued, Date patent was filed, Title of the patent, Applicant, Inventor, Assignee, Attorney firm, Primary examiner, Assistant examiner, CPCs, and Abstract. The patent badge does contain a link to the full patent document (in Adobe Acrobat format, aka pdf). To download or print any patent click here.

Date of Patent:
Oct. 25, 1988

Filed:

Mar. 28, 1985
Applicant:
Inventors:

Christoph Heusser, Bottmingen, CH;

Rudolf H Andreatta, Allschwil, CH;

Sefik Alkan, Riehen, CH;

Jeanette Wood, Biel-Benken, CH;

Assignee:

Ciba-Geigy Corporation, Ardsley, NY (US);

Attorneys:
Primary Examiner:
Assistant Examiner:
Int. Cl.
CPC ...
G01N / ; G01N / ; C12N / ;
U.S. Cl.
CPC ...
435-7 ; 435 68 ; 4351722 ; 435810 ; 424 858 ; 424 88 ; 436518 ; 436548 ; 436808 ; 436815 ; 530387 ; 530388 ; 530808 ; 935 89 ; 935 93 ; 935104 ; 935106 ; 935107 ; 935108 ; 935110 ;
Abstract

The invention relates to novel monoclonal antibodies having a high affinity for human renin, derivatives thereof, processes for the preparation of these antibodies and their derivatives, hybridoma cell lines that produce these antibodies, and to processes for the preparation of said hybridoma cells lines. The monoclonal antibodies according to the invention and their derivatives can be used for the qualitative and quantitative determination of human renin and structurally similar renin, for the purification of human renin and structurally similar renin and for the treatment of high blood pressure and cardiac insufficiency.


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