The patent badge is an abbreviated version of the USPTO patent document. The patent badge does contain a link to the full patent document.

The patent badge is an abbreviated version of the USPTO patent document. The patent badge covers the following: Patent number, Date patent was issued, Date patent was filed, Title of the patent, Applicant, Inventor, Assignee, Attorney firm, Primary examiner, Assistant examiner, CPCs, and Abstract. The patent badge does contain a link to the full patent document (in Adobe Acrobat format, aka pdf). To download or print any patent click here.

Date of Patent:
Oct. 18, 1988

Filed:

Jun. 18, 1987
Applicant:
Inventors:

Julian Adams, Westmount, CA;

Yvan Guindon, Montreal, CA;

Patrice C Belanger, Dollard des Ormeaux, CA;

Michel L Belley, St. Laurent, CA;

Joshua Rokach, Chomedey, CA;

Assignee:
Attorneys:
Primary Examiner:
Assistant Examiner:
Int. Cl.
CPC ...
A61K / ; C07D / ;
U.S. Cl.
CPC ...
514320 ; 514422 ; 514452 ; 514456 ; 514464 ; 514469 ; 514470 ; 546196 ; 548525 ; 549362 ; 549398 ; 549435 ; 549466 ; 549467 ; 549468 ; 549469 ; 549470 ;
Abstract

4,7-Benzofurandione derivatives of Formula I, pharmaceutical compositions, and methods of treatment are disclosed. These compounds are useful as inhibitors of mammalian leukotriene biosynthesis. As such, these compounds are useful therapeutic agents for treating allergic conditions, asthma, cardiovascular disorders, inflammation, psoriasis and allergic conjunctivitis. The compounds are also useful as analgesics and as cytoprotective agents. Also disclosed are novel intermediates useful for the preparation of the 4,7-benzofurandiones of this invention. ##STR1##


Find Patent Forward Citations

Loading…