The patent badge is an abbreviated version of the USPTO patent document. The patent badge does contain a link to the full patent document.
The patent badge is an abbreviated version of the USPTO patent document. The patent badge covers the following: Patent number, Date patent was issued, Date patent was filed, Title of the patent, Applicant, Inventor, Assignee, Attorney firm, Primary examiner, Assistant examiner, CPCs, and Abstract. The patent badge does contain a link to the full patent document (in Adobe Acrobat format, aka pdf). To download or print any patent click here.
Patent No.:
Date of Patent:
Sep. 20, 1988
Filed:
Jan. 13, 1986
Applicant:
Inventors:
James N Wemple, Holland, MI (US);
James R Zeller, Holland, MI (US);
John M Domagala, Canton, MI (US);
Assignee:
Warner-Lambert Company, Morris Plains, NJ (US);
Attorney:
Primary Examiner:
Assistant Examiner:
Int. Cl.
CPC ...
C07D / ; C07D / ; C07D / ; C07D / ;
U.S. Cl.
CPC ...
544349 ; 544-3 ; 544 53 ; 544 54 ; 544 55 ; 544 56 ; 544 582 ; 544 586 ; 544 62 ; 544 63 ; 544 96 ; 544 98 ; 544128 ; 544238 ; 544333 ; 544336 ; 544351 ; 544363 ; 546 15 ; 546 16 ; 546113 ; 546122 ; 546126 ; 546153 ; 546156 ; 558389 ; 560 51 ;
Abstract
An improved process for the preparation of 7-substituted amino-1-alkyl- or cyclopropyl-6,8-difluoro-1,4-dihydro-4-oxo-3-quinolinecarboxylic acids is described where tetrafluorobenzoyl chloride is converted in three operations via 1-alkyl or 1-cycloalkyl-1,4-dihydro-6,7,8-trifluoro-4-oxoquinoline-3-carbonitrile which in a separate step or in situ is displaced and hydrolyzed to the desired product.