The patent badge is an abbreviated version of the USPTO patent document. The patent badge does contain a link to the full patent document.
The patent badge is an abbreviated version of the USPTO patent document. The patent badge covers the following: Patent number, Date patent was issued, Date patent was filed, Title of the patent, Applicant, Inventor, Assignee, Attorney firm, Primary examiner, Assistant examiner, CPCs, and Abstract. The patent badge does contain a link to the full patent document (in Adobe Acrobat format, aka pdf). To download or print any patent click here.
Patent No.:
Date of Patent:
Sep. 06, 1988
Filed:
Jan. 13, 1987
Kouji Ishihara, Saitama, JP;
Mika Sanada, Tokyo, JP;
Naoki Matsuo, Ibaraki, JP;
Yoshimitsu Iida, Saitama, JP;
Yoshinori Matsuoka, Ibaraki, JP;
Junko Matsuo, Ibaraki, JP;
Chugai Seiyaku Kabushiki Kaisha, Tokyo, JP;
Abstract
A non-liquid type preparation for injection that has improved stability contains N-(2-hydroxyethyl)-nicotinamide nitrate ester (generally known as nicorandil) and an inorganic or organic acid and/or an alkaline metal salt thereof. These ingredients, together with an excipient that is pharmaceutically acceptable, may be dissolved in a solvent, sterilized by filtration and freeze-dried to obtain a freeze-dried preparation, or may be dissolved in a solvent under an aseptic condition and recrystallized to obtain an injectable powder. Nicorandil preparations according to the present invention are very stable and useful in clinical applications.