The patent badge is an abbreviated version of the USPTO patent document. The patent badge does contain a link to the full patent document.
The patent badge is an abbreviated version of the USPTO patent document. The patent badge covers the following: Patent number, Date patent was issued, Date patent was filed, Title of the patent, Applicant, Inventor, Assignee, Attorney firm, Primary examiner, Assistant examiner, CPCs, and Abstract. The patent badge does contain a link to the full patent document (in Adobe Acrobat format, aka pdf). To download or print any patent click here.
Patent No.:
Date of Patent:
Aug. 23, 1988
Filed:
Oct. 06, 1987
Applicant:
Inventors:
Mark J D'Andrea, Neshanic Station, NJ (US);
Stanley J Tarnowski, Jr, Sunnyvale, CA (US);
Arthur D Clark, Jr, Princeton, NJ (US);
Assignee:
Interferon Sciences, Inc., New Brunswick, NJ (US);
Attorney:
Primary Examiner:
Int. Cl.
CPC ...
B01D / ; C07K / ; A61K / ;
U.S. Cl.
CPC ...
210635 ; 210656 ; 424 85 ; 435803 ; 435808 ; 530351 ; 530413 ; 530417 ;
Abstract
Fast moving monomers of alpha-2 interferon ('IFN-alpha-2') are purified from slow moving monomers and oligomers of interferon and from noninterferon proteins using a combination of immunoaffinity chromatography, reverse phase HPLC, cation exchange chromatography, and gel filtration. Two fast monomer forms, FMM.sub.1 and FMM.sub.2, are further distinguished on the basis of charge and hydrophobicity and FMM.sub.2 is obtained in essentially homogeneous form with respect to size, hydrophobicity and charge.