The patent badge is an abbreviated version of the USPTO patent document. The patent badge does contain a link to the full patent document.
The patent badge is an abbreviated version of the USPTO patent document. The patent badge covers the following: Patent number, Date patent was issued, Date patent was filed, Title of the patent, Applicant, Inventor, Assignee, Attorney firm, Primary examiner, Assistant examiner, CPCs, and Abstract. The patent badge does contain a link to the full patent document (in Adobe Acrobat format, aka pdf). To download or print any patent click here.
Patent No.:
Date of Patent:
Jul. 26, 1988
Filed:
Sep. 09, 1985
Applicant:
Inventors:
Pamela A Chambers, St. Davids, PA (US);
James S Frazee, Collingswood, NJ (US);
Carl Kaiser, Haddon Heights, NJ (US);
Lawrence I Kruse, Haddonfield, NJ (US);
Assignee:
SmithKline Beckman Corporation, Philadelphia, PA (US);
Primary Examiner:
Int. Cl.
CPC ...
A01K / ; C07C / ;
U.S. Cl.
CPC ...
514523 ; 558406 ; 558408 ; 560 55 ; 568441 ;
Abstract
Potent, irreversible dopamine-.beta.-hydroxylase inhibitors having the Formula: ##STR1## which are useful to inhibit dopamine-.beta.-hydroxylase activity, pharmaceutical compositions including these inhibitors or 2-cyano-2-phenethylamine, and methods of using these inhibitors or 2-cyano-2-phenethylamine to inhibit dopamine-.beta.-hydroxylase activity in mammals. Also disclosed are novel intermediates useful in preparing the presently invented inhibitors.