The patent badge is an abbreviated version of the USPTO patent document. The patent badge does contain a link to the full patent document.
The patent badge is an abbreviated version of the USPTO patent document. The patent badge covers the following: Patent number, Date patent was issued, Date patent was filed, Title of the patent, Applicant, Inventor, Assignee, Attorney firm, Primary examiner, Assistant examiner, CPCs, and Abstract. The patent badge does contain a link to the full patent document (in Adobe Acrobat format, aka pdf). To download or print any patent click here.
Patent No.:
Date of Patent:
Jul. 19, 1988
Filed:
Feb. 13, 1987
Donald W Hansen, Jr, Chicago, IL (US);
Barnett S Pitzele, Skokie, IL (US);
Robert W Hamilton, Wilmette, IL (US);
Michael Clare, Skokie, IL (US);
G. D. Searle & Co., Chicago, IL (US);
Abstract
This invention relates to novel 3-thiophene-substituted tryosyl dipeptide amides of the formula: ##STR1## and the pharmaceutically acceptable addition salts thereof, wherein R.sup.1 is --OH, benzyloxy, or --OCH.sub.3 ; wherein R.sub.2 and R.sub.3 may be the same or different and represent lower alkyl of 1-6 carbon atoms; wherein R.sup.4, R.sup.5, R.sup.6, R.sup.7, R.sup.8, and R.sup.9 may be the same or different and represent hydrogen or lower alkyl of 1-6 carbon atoms; wherein 'v' represents an asymmetric carbon atom that may be racemic or that may have the D or L configuration; and wherein 'w' represents an asymmetric carbon atom that has the D configuration. These compounds are useful as analgesic agents.