The patent badge is an abbreviated version of the USPTO patent document. The patent badge does contain a link to the full patent document.
The patent badge is an abbreviated version of the USPTO patent document. The patent badge covers the following: Patent number, Date patent was issued, Date patent was filed, Title of the patent, Applicant, Inventor, Assignee, Attorney firm, Primary examiner, Assistant examiner, CPCs, and Abstract. The patent badge does contain a link to the full patent document (in Adobe Acrobat format, aka pdf). To download or print any patent click here.
Patent No.:
Date of Patent:
Jul. 05, 1988
Filed:
Mar. 27, 1986
Applicant:
Inventor:
Stanley J Cryz, Bolligen, CH;
Assignee:
Swiss Serum and Vaccine Institute Berne, Berne, CH;
Attorney:
Primary Examiner:
Int. Cl.
CPC ...
C08B / ; A61K / ; A61K / ;
U.S. Cl.
CPC ...
424 92 ; 435852 ; 536-11 ; 536123 ; 536127 ; 536128 ;
Abstract
The present invention relates to immunogenic preparations of Klebsiella species serotype-specific capsular polysaccharides. The invention involves the treatment of Klebsiella capsular polysaccharides in dilute sodium hydroxide to detoxify co-purified toxic lipopolysaccharides and to yield immunogenic vaccine preparations safe for parenteral administration to humans. The polyvalent vaccines prepared by use of the above vaccine are effective at providing protection against infections caused by Klebsiella species bacilli.