The patent badge is an abbreviated version of the USPTO patent document. The patent badge does contain a link to the full patent document.
The patent badge is an abbreviated version of the USPTO patent document. The patent badge covers the following: Patent number, Date patent was issued, Date patent was filed, Title of the patent, Applicant, Inventor, Assignee, Attorney firm, Primary examiner, Assistant examiner, CPCs, and Abstract. The patent badge does contain a link to the full patent document (in Adobe Acrobat format, aka pdf). To download or print any patent click here.
Patent No.:
Date of Patent:
Jun. 28, 1988
Filed:
Jul. 08, 1985
Applicant:
Inventor:
Michele P Calos, Stanford, CA (US);
Assignee:
Board of Trustees of the Leland Stanford Junior University, Stanford, CA (US);
Attorney:
Primary Examiner:
Assistant Examiner:
Int. Cl.
CPC ...
C12N / ; C12N / ; C12Q / ;
U.S. Cl.
CPC ...
435-6 ; 435 29 ; 435 32 ; 435 34 ; 4351721 ; 4353171 ; 536 27 ; 935 24 ; 935 33 ; 935 79 ;
Abstract
Mutagenic capability is determined by employing a shuttle vector having prokaryotic and eukaryotic origins, a prokaryotic marker an a gene capable of screening or selection in a prokaryote. The method involves introducing the vector into mammalian cells, exposing the cells to the candidate to be tested for mutagenicity for a time sufficient to allow lesions to occur, rescuing the vector by transforming into a prokaryotic host and screening for mutations of the gene.