The patent badge is an abbreviated version of the USPTO patent document. The patent badge does contain a link to the full patent document.
The patent badge is an abbreviated version of the USPTO patent document. The patent badge covers the following: Patent number, Date patent was issued, Date patent was filed, Title of the patent, Applicant, Inventor, Assignee, Attorney firm, Primary examiner, Assistant examiner, CPCs, and Abstract. The patent badge does contain a link to the full patent document (in Adobe Acrobat format, aka pdf). To download or print any patent click here.
Patent No.:
Date of Patent:
Jun. 14, 1988
Filed:
Feb. 05, 1985
Hermanus J Kempen, Leiden, NL;
Abstract
Synthetic glycolipides having the general formula lipidyl-O-R wherein the lipidyl moiety is selected from the group consisting of 5-cholestene-3.beta.-yl, ceramidyl, phosphatidylethanolamine and diacylglycerol and R represents a group having the formula ##STR1## in which two symbols Z represent a glycopyranosyl rest and the other symbol Z a hydrogen atom or all three symbols Z represent a glycopyranosyl rest. These new glycolipides can be used for the solubilization of cholesterol in water or aqueous media, for the manufacture of lipide-vesicles or lipoproteins in which such a glycolipide is encapsulated as well as for the reduction of the cholesterol level in the blood plasma of mammals. Preferably the compound N-tris(.beta.-D-galactopyranosyloxymethyl)methyl-N.alpha.-(4-(5 cholesten-3.beta.-yloxy)succinyl)glycinamide is used.