The patent badge is an abbreviated version of the USPTO patent document. The patent badge does contain a link to the full patent document.
The patent badge is an abbreviated version of the USPTO patent document. The patent badge covers the following: Patent number, Date patent was issued, Date patent was filed, Title of the patent, Applicant, Inventor, Assignee, Attorney firm, Primary examiner, Assistant examiner, CPCs, and Abstract. The patent badge does contain a link to the full patent document (in Adobe Acrobat format, aka pdf). To download or print any patent click here.
Patent No.:
Date of Patent:
Jun. 07, 1988
Filed:
Jul. 10, 1987
Applicant:
Inventors:
Kuniyoshi Masuzawa, Koga, JP;
Kyuya Okamura, Ohmiya, JP;
Shizuyoshi Fujimori, Tochigi, JP;
Susumu Kinoshita, Okaya, JP;
Hiroshi Matsukubo, Okaya, JP;
Assignee:
Kyorin Pharmaceutical Co., Ltd., Tokyo, JP;
Primary Examiner:
Assistant Examiner:
Int. Cl.
CPC ...
C07D / ; C07D / ; C07D / ;
U.S. Cl.
CPC ...
544-6 ; 544 70 ; 544230 ; 546 15 ;
Abstract
This invention relates to novel processes for the manufacture of spiro-linked pyrrolidine-2,5-diones of the formula; ##STR1## which have a potent inhibitory activity on aldose reductase and are useful for reduction and prevention of chronic diabetic complications. The invented processes are useful as improved and convenient method for a large scale manufacture.