The patent badge is an abbreviated version of the USPTO patent document. The patent badge does contain a link to the full patent document.
The patent badge is an abbreviated version of the USPTO patent document. The patent badge covers the following: Patent number, Date patent was issued, Date patent was filed, Title of the patent, Applicant, Inventor, Assignee, Attorney firm, Primary examiner, Assistant examiner, CPCs, and Abstract. The patent badge does contain a link to the full patent document (in Adobe Acrobat format, aka pdf). To download or print any patent click here.
Patent No.:
Date of Patent:
Apr. 05, 1988
Filed:
Dec. 28, 1984
Applicant:
Inventor:
Levy Kopelovich, St. Petersburg, FL (US);
Assignee:
Oncotech, Inc., Wilmington, DE (US);
Attorney:
Primary Examiner:
Int. Cl.
CPC ...
C12Q / ; C12Q / ;
U.S. Cl.
CPC ...
435-5 ; 435 26 ; 435 29 ; 43524023 ; 436813 ;
Abstract
The present invention relates to an improved viral transformation/neodifferentiation assay for determining predisposition to cancer. The invention is based on the association between retroviral transformation/neodifferentiation and a predisposition to cancer. The level of lipogenic enzymes is measured in cultured human fibroblast cells after transformation/neodifferentiation with Kirsten murine sarcoma virus in the presence of glucocorticosteroids to monitor the extent of conversion of the human skin fibroblasts to fully mature adipocytes.