The patent badge is an abbreviated version of the USPTO patent document. The patent badge does contain a link to the full patent document.
The patent badge is an abbreviated version of the USPTO patent document. The patent badge covers the following: Patent number, Date patent was issued, Date patent was filed, Title of the patent, Applicant, Inventor, Assignee, Attorney firm, Primary examiner, Assistant examiner, CPCs, and Abstract. The patent badge does contain a link to the full patent document (in Adobe Acrobat format, aka pdf). To download or print any patent click here.
Patent No.:
Date of Patent:
Mar. 29, 1988
Filed:
Nov. 27, 1984
Applicant:
Inventors:
Nanibhushan Dattagupta, New Haven, CT (US);
Peter M Rae, Hamden, CT (US);
Donald M Crothers, Northford, CT (US);
Thomas R Barnett, East Haven, CT (US);
Assignee:
Molecular Diagnostics, Inc., West Haven, CT (US);
Attorney:
Primary Examiner:
Int. Cl.
CPC ...
C12P / ; C12Q / ;
U.S. Cl.
CPC ...
435 91 ; 435-6 ; 935-2 ; 935 78 ; 536 27 ;
Abstract
A process for production of a single strand of a nucleic acid comprising covalently linking to a solid substrate a polynucleotide complementary to the desired strand, hybridizing said polynucleotide with an oligonucleotide, extending the oligonucleotide in direction away from said substrate, denaturing the hybridized polynucleotide and extended oligonucleotide, thereby to free the extended oligonucleotide from the solid substrate, and separating the extended oligonucleotide. The product can be used for making analytical probes.