The patent badge is an abbreviated version of the USPTO patent document. The patent badge does contain a link to the full patent document.
The patent badge is an abbreviated version of the USPTO patent document. The patent badge covers the following: Patent number, Date patent was issued, Date patent was filed, Title of the patent, Applicant, Inventor, Assignee, Attorney firm, Primary examiner, Assistant examiner, CPCs, and Abstract. The patent badge does contain a link to the full patent document (in Adobe Acrobat format, aka pdf). To download or print any patent click here.
Patent No.:
Date of Patent:
Mar. 22, 1988
Filed:
Dec. 31, 1984
Applicant:
Inventors:
Thomas B Tomasi, Corrales, NM (US);
William L Anderson, Albuquerque, NM (US);
Assignee:
University of New Mexico, Albuquerque, NM (US);
Primary Examiner:
Int. Cl.
CPC ...
G01N / ; G01N / ; G01N / ; G01N / ;
U.S. Cl.
CPC ...
436547 ; 424-11 ; 424-9 ; 436548 ; 436804 ; 436813 ; 530387 ;
Abstract
PEG-modified protein molecules characterized by reduced immunogenicity are prepared by covalent modification of the protein with PEG employing an active ester intermediate. Antibodies so modified exhibit decreased binding capacity for Fc cell surface receptors, are non-toxic and retain full antigen binding activity, and are consequently useful in a variety of immunologically-based diagnostic and therapeutic procedures.