The patent badge is an abbreviated version of the USPTO patent document. The patent badge does contain a link to the full patent document.

The patent badge is an abbreviated version of the USPTO patent document. The patent badge covers the following: Patent number, Date patent was issued, Date patent was filed, Title of the patent, Applicant, Inventor, Assignee, Attorney firm, Primary examiner, Assistant examiner, CPCs, and Abstract. The patent badge does contain a link to the full patent document (in Adobe Acrobat format, aka pdf). To download or print any patent click here.

Date of Patent:
Mar. 15, 1988

Filed:

Jun. 04, 1984
Applicant:
Inventors:

Russell E Thompson, Marshfield, MA (US);

Robert H Rubin, Brookline, MA (US);

Nina T Rubin, Brookline, MA (US);

Teresa H Chan, Burlington, MA (US);

Assignee:

Ortho Diagnostic Systems Inc., Raritan, NJ (US);

Attorney:
Primary Examiner:
Int. Cl.
CPC ...
G01N / ; G01N / ; G01N / ; G01N / ;
U.S. Cl.
CPC ...
435-7 ; 4351722 ; 43524027 ; 436520 ; 436526 ; 436531 ; 436534 ; 436548 ; 436804 ; 436813 ;
Abstract

Methods are provided for the detection of proximal convoluted tubule causing diseases or kidney harmful drug monitoring by detecting the presence of shed normal proximal tubule associated antigens in a body fluid such as urine. The preferred embodiment employs an ELISA sandwich format wherein one monoclonal antibody specific for a first epitopic site on said antigen is immobilized on a solid phase and a second antibody, specific for a second epitopic site on said antigen is directly or indirectly labeled.


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