The patent badge is an abbreviated version of the USPTO patent document. The patent badge does contain a link to the full patent document.
The patent badge is an abbreviated version of the USPTO patent document. The patent badge covers the following: Patent number, Date patent was issued, Date patent was filed, Title of the patent, Applicant, Inventor, Assignee, Attorney firm, Primary examiner, Assistant examiner, CPCs, and Abstract. The patent badge does contain a link to the full patent document (in Adobe Acrobat format, aka pdf). To download or print any patent click here.
Patent No.:
Date of Patent:
Mar. 08, 1988
Filed:
Jan. 03, 1984
Applicant:
Inventors:
Peter Ralph, Purdys, NY (US);
Karl Welte, New York, NY (US);
Assignee:
Sloan-Kettering Institute for Cancer Research, New York, NY (US);
Attorney:
Primary Examiner:
Int. Cl.
CPC ...
C07K / ; C12P / ; C12N / ;
U.S. Cl.
CPC ...
530351 ; 435-7 ; 435 68 ; 43524027 ; 530412 ; 530416 ; 530417 ;
Abstract
Highly purified T cell replacing factor (TRF or BIF) essentially free of IL-2 and Interferon activities is obtained in the invention. BIF is useful for treatment of immunoregulatory disorders and/or stimulation of production of immunoglobulins. A method for production of BIF and BGF is described. B cell lines for BIF assays are described as well as an assay for B cell receptor variants and a method for obtaining B cell variants from a variety of source materials.