The patent badge is an abbreviated version of the USPTO patent document. The patent badge does contain a link to the full patent document.

The patent badge is an abbreviated version of the USPTO patent document. The patent badge covers the following: Patent number, Date patent was issued, Date patent was filed, Title of the patent, Applicant, Inventor, Assignee, Attorney firm, Primary examiner, Assistant examiner, CPCs, and Abstract. The patent badge does contain a link to the full patent document (in Adobe Acrobat format, aka pdf). To download or print any patent click here.

Date of Patent:
Mar. 01, 1988

Filed:

Jun. 11, 1984
Applicant:
Inventors:

Duncan H Haynes, Miami, FL (US);

Wenche Jy, Miami, FL (US);

Yeon S Ahn, Miami, FL (US);

William J Harrington, Miami, FL (US);

Assignee:

University of Miami, Coral Gables, FL (US);

Attorney:
Primary Examiner:
Assistant Examiner:
Int. Cl.
CPC ...
A61K / ; G01N / ; C12Q / ;
U.S. Cl.
CPC ...
514356 ; 514824 ; 514929 ; 435-2 ; 435 13 ; 435 29 ; 436 63 ;
Abstract

Calcium (Ca.sup.2+) channel blockers, such as nifedipine and verapamil, are used in the treatment of thromboembolic diseases such as stroke and peripheral vascular occlusive diseases, especially arterial and venous thrombosis, vasculitis, myelofibrosis disease and hemolytic anemias. Such diseases arise from platelet hyperactivation and the Ca.sup.2+ channel blockers restore the platelets to their normal aggregation characteristics. Diagnostic procedures for detecting platelet hyperactivation and defective calcium handling/transport indicative of certain peripheral obstructive diseases using chlorotetracycline as a detectable fluorescent probe as a means of assessing a patient's response to Ca.sup.2+ channel blockers in the therapy of such diseases are also described.


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Haynes, Duncan. (1988). Method of treating diseases arising from platelet hyperactivation (U.S. Patent No. 4728660). U.S. Patent and Trademark Office. https://idiyas.com/patent/badge/4728660

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