The patent badge is an abbreviated version of the USPTO patent document. The patent badge does contain a link to the full patent document.

The patent badge is an abbreviated version of the USPTO patent document. The patent badge covers the following: Patent number, Date patent was issued, Date patent was filed, Title of the patent, Applicant, Inventor, Assignee, Attorney firm, Primary examiner, Assistant examiner, CPCs, and Abstract. The patent badge does contain a link to the full patent document (in Adobe Acrobat format, aka pdf). To download or print any patent click here.

Date of Patent:
Mar. 01, 1988

Filed:

Sep. 24, 1985
Applicant:
Inventors:

Ram S Bhatt, Nutley, NJ (US);

Kenneth J Collier, Rockaway, NJ (US);

Robert M Crowl, Little Falls, NJ (US);

Mohindar S Poonian, West Caldwell, NJ (US);

Assignee:

Hoffmann-La-Roche Inc., Nutley, NJ (US);

Attorneys:
Primary Examiner:
Int. Cl.
CPC ...
C12P / ; C12P / ; C12N / ; C12N / ; C12N / ; C07H / ;
U.S. Cl.
CPC ...
435 68 ; 435 70 ; 4351723 ; 435253 ; 435320 ; 935 13 ; 536 27 ;
Abstract

Th preparation of a double-stranded polydeoxy ribonucleotide having cohesive termini each comprising one strand of a double-strand restriction endonuclease recognition site and, between the termini, a structural gene coating for the expression of recombinant growth hormone releasing factor, at least a majority of the codons and the coding strand of said gene being codons preferred for the expression of microbial genomes; a method of producing such DNA a recombinant microbial cloning vehicle comprising such DNA and the novel methods of producing said peptide are described.


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