The patent badge is an abbreviated version of the USPTO patent document. The patent badge does contain a link to the full patent document.

The patent badge is an abbreviated version of the USPTO patent document. The patent badge covers the following: Patent number, Date patent was issued, Date patent was filed, Title of the patent, Applicant, Inventor, Assignee, Attorney firm, Primary examiner, Assistant examiner, CPCs, and Abstract. The patent badge does contain a link to the full patent document (in Adobe Acrobat format, aka pdf). To download or print any patent click here.

Date of Patent:
Jan. 19, 1988

Filed:

May. 20, 1985
Applicant:
Inventor:

Kenneth J Lembach, Danville, CA (US);

Assignee:

Miles Laboratories, Inc., Elkhart, IN (US);

Attorneys:
Primary Examiner:
Int. Cl.
CPC ...
A61K / ; A61K / ; A61K / ; A61K / ; A61K / ; A61K / ;
U.S. Cl.
CPC ...
424 86 ; 424 85 ; 424 87 ; 424 88 ; 424 89 ; 424 92 ; 424 93 ; 514-2 ; 514 21 ; 514802 ; 530364 ; 530380 ; 530381 ; 530382 ; 530383 ; 530384 ; 530386 ; 530387 ; 530389 ; 530390 ; 530392 ; 530393 ; 530397 ; 530403 ; 530404 ; 530405 ; 530408 ; 530410 ; 530806 ; 530825 ; 530826 ; 435177 ; 435188 ;
Abstract

Compositions containing therapeutically or immunologically active proteins are rendered substantially free from infectious agents such as viable viruses and bacteria without substantial loss of therapeutic or immunologic activity by mixing the protein composition with a complex formed from transition metal ions, such as copper ions, and an angularly-fused, polynuclear heterocyclic arene having two nitrogen atoms in a 'cis-ortho' relationship, such as phenanthroline, and a reducing agent such as a thiol or ascorbic acid or ascorbate salt or mixtures of ascorbic acid or ascorbate with a thiol in amounts and at a temperature and for a time sufficient to inactivate substantially all of the viruses and bacteria contained therein. Compositions containing therapeutically active proteins substantially free from viral and bacterial infectivity, which have heretofore been unattainable, can be prepared by the method of the invention.


Find Patent Forward Citations

Lembach, Kenneth. (1988). Protein compositions substantially free from infectious agents (U.S. Patent No. 4720385). U.S. Patent and Trademark Office. https://idiyas.com/patent/badge/4720385

Data source: USPTO (United States Patent and Trademark Office) public patent records. Weekly synchronization. How IDiyas builds this profile

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