The patent badge is an abbreviated version of the USPTO patent document. The patent badge does contain a link to the full patent document.
The patent badge is an abbreviated version of the USPTO patent document. The patent badge covers the following: Patent number, Date patent was issued, Date patent was filed, Title of the patent, Applicant, Inventor, Assignee, Attorney firm, Primary examiner, Assistant examiner, CPCs, and Abstract. The patent badge does contain a link to the full patent document (in Adobe Acrobat format, aka pdf). To download or print any patent click here.
Patent No.:
Date of Patent:
Dec. 29, 1987
Filed:
May. 08, 1987
John N Dukes, Los Altos Hills, CA (US);
William F Carlsen, Jr, Mountain View, CA (US);
Richard J Pittaro, San Carlos, CA (US);
Hewlett-Packard Company, Palo Alto, CA (US);
Abstract
Oxygen determination based on luminescence quenching of fluorescent dye is effected by using the frequency output of an offset-phase locked loop to calculate the time constant for the exponential decay of fluorescence. An offset phase angle between a periodic stimulus signal used to excite the dye and a response signal based on fluorescence detection is predetermined to optimize signal-to-noise ratio for a wide range of time constants. An offset-phase locked loop is used to vary the frequency of a periodic stimulus signal until the predetermined phase relationship is established. Where the stimulus and response signals are substantially sinusoidal, the offset phase angle is ideally about 49.3.degree., although substantially optimal performance is achieved using a more conveniently generated 45.degree.. The 45.degree. angle offset can also be used with a square-wave stimulus signal.