The patent badge is an abbreviated version of the USPTO patent document. The patent badge does contain a link to the full patent document.
The patent badge is an abbreviated version of the USPTO patent document. The patent badge covers the following: Patent number, Date patent was issued, Date patent was filed, Title of the patent, Applicant, Inventor, Assignee, Attorney firm, Primary examiner, Assistant examiner, CPCs, and Abstract. The patent badge does contain a link to the full patent document (in Adobe Acrobat format, aka pdf). To download or print any patent click here.
Patent No.:
Date of Patent:
Dec. 01, 1987
Filed:
Aug. 21, 1985
Applicant:
Inventors:
Knut Bartl, Wilzhofen, DE;
Helmut Lill, Wielenbach, DE;
Assignee:
Boehringer Mannheim GmbH, Mannheim, DE;
Attorney:
Primary Examiner:
Int. Cl.
CPC ...
C12Q / ; C12N / ; C12N / ;
U.S. Cl.
CPC ...
435 13 ; 435214 ; 435217 ; 435810 ; 436 63 ; 436 69 ;
Abstract
The present invention provides a process for the determination of fibrin monomer in plasma, wherein a plasma sample containing fibrin monomer and freed from plasmin inhibitors is incubated in buffered solution with tissue plasminogen activator (EPA), plasminogen and a chromogenic plasmin substrate and the color formed is measured as a measure of the amount of fibrin monomer. The present invention also provides a reagent for the determination of fibrin monomer in plasma, wherein it contains plasminogen, tissue plasminogen activator (EPA), chromogenic plasmin substrate and buffer (pH 7.0 to 9.0).