The patent badge is an abbreviated version of the USPTO patent document. The patent badge does contain a link to the full patent document.
The patent badge is an abbreviated version of the USPTO patent document. The patent badge covers the following: Patent number, Date patent was issued, Date patent was filed, Title of the patent, Applicant, Inventor, Assignee, Attorney firm, Primary examiner, Assistant examiner, CPCs, and Abstract. The patent badge does contain a link to the full patent document (in Adobe Acrobat format, aka pdf). To download or print any patent click here.
Patent No.:
Date of Patent:
Nov. 24, 1987
Filed:
May. 30, 1986
Applicant:
Inventor:
Yoshinobu Nagano, Tokyo, JP;
Assignee:
Yamanouchi Pharmaceutical Co., Ltd., Tokyo, JP;
Attorney:
Primary Examiner:
Int. Cl.
CPC ...
C07K / ; C07K / ;
U.S. Cl.
CPC ...
530332 ; 530331 ;
Abstract
Sulfates of glutathione monoalkyl esters (alkyl.gamma.-L-glutamyl-L-cysteinylglycinates) are new and can be prepared by reaction of glutathione with an alcohol in the presence of sulfuric acid. This process forms virtually no diesters, which are toxic compounds and must be completely removed when the sulfates are used as medicine. In addition, since pure glutathione monoester sulfates can be isolated from reaction mixture, high-purity free glutathione monoesters, which have importance as therapeutical and preventive medicines, can be obtained by treatment with a neutralizer or by mere desalting.