The patent badge is an abbreviated version of the USPTO patent document. The patent badge does contain a link to the full patent document.

The patent badge is an abbreviated version of the USPTO patent document. The patent badge covers the following: Patent number, Date patent was issued, Date patent was filed, Title of the patent, Applicant, Inventor, Assignee, Attorney firm, Primary examiner, Assistant examiner, CPCs, and Abstract. The patent badge does contain a link to the full patent document (in Adobe Acrobat format, aka pdf). To download or print any patent click here.

Date of Patent:
Nov. 24, 1987

Filed:

Jun. 27, 1986
Applicant:
Inventors:

Maurice E Loomans, Cincinnati, OH (US);

Randall S Matthews, Cincinnati, OH (US);

Joseph A Miller, Fairfield, OH (US);

Assignee:

The Procter & Gamble Company, Cincinnati, OH (US);

Attorneys:
Primary Examiner:
Int. Cl.
CPC ...
A61K / ;
U.S. Cl.
CPC ...
514689 ; 560142 ; 560130 ; 558415 ; 558416 ; 558427 ; 558436 ; 558441 ; 568775 ; 568784 ; 568308 ; 568337 ; 568662 ; 568663 ; 568627 ; 564342 ; 564366 ; 564372 ; 564374 ; 564285 ; 564223 ; 564169 ; 2604105 ; 562463 ; 514545 ; 514546 ; 514733 ; 514678 ; 514649 ; 514643 ; 514629 ; 514621 ; 514570 ;
Abstract

The present invention relates to novel specifically-substituted phenyl compounds, especially substituted di-tert-butyl phenol derivatives, which are effective as anti-inflammatory, analgesic and/or antipyretic agents. These phenyl compounds are substituted with a low molecular weight alkyl chain which terminates in a specific unsaturated functional group. These unsaturated functionalities are --C.tbd.CH, C.dbd.CH.sub.2, C.dbd.C.dbd.CH.sub.2, and aldehydes in the form of their acetals. The present invention further relates to pharmaceutical compositions which contain an anti-inflammatory agent of the present invention and a pharmaceutically-acceptable carrier. Finally, the present invention relates to methods for treating diseases characterized by inflammation, such as rheumatoid arthritis and osteoarthritis, in humans or lower animals. Such methods comprise administering to a human or lower animal in need of such treatment a safe and effective amount of an anti-inflammatory agent or composition of the present invention.


Find Patent Forward Citations

Loading…