The patent badge is an abbreviated version of the USPTO patent document. The patent badge does contain a link to the full patent document.
The patent badge is an abbreviated version of the USPTO patent document. The patent badge covers the following: Patent number, Date patent was issued, Date patent was filed, Title of the patent, Applicant, Inventor, Assignee, Attorney firm, Primary examiner, Assistant examiner, CPCs, and Abstract. The patent badge does contain a link to the full patent document (in Adobe Acrobat format, aka pdf). To download or print any patent click here.
Patent No.:
Date of Patent:
Nov. 10, 1987
Filed:
May. 09, 1986
Applicant:
Inventors:
Jane V Scott, Chappaqua, NY (US);
Joseph F Waggett, New City, NY (US);
Assignee:
American Cyanamid, Stamford, CT (US);
Attorney:
Primary Examiner:
Int. Cl.
CPC ...
C12N / ; A61K / ; A61K / ;
U.S. Cl.
CPC ...
424 92 ; 435253 ; 530825 ;
Abstract
This invention discloses a process for preparing an acellular Bordetella pertussis vaccine by passing culture supernatants or cellular extracts of B. pertussis through a column containing an ion exchange resin. The eluate from the column is detoxified and can then be employed by conventional means as a vaccine. The vaccine so produced has reduced toxicity due to the removal of endotoxin.