The patent badge is an abbreviated version of the USPTO patent document. The patent badge does contain a link to the full patent document.

The patent badge is an abbreviated version of the USPTO patent document. The patent badge covers the following: Patent number, Date patent was issued, Date patent was filed, Title of the patent, Applicant, Inventor, Assignee, Attorney firm, Primary examiner, Assistant examiner, CPCs, and Abstract. The patent badge does contain a link to the full patent document (in Adobe Acrobat format, aka pdf). To download or print any patent click here.

Date of Patent:
Nov. 03, 1987

Filed:

Mar. 17, 1986
Applicant:
Inventors:

Orhideya B Zabunova, Sofia, BG;

Hristo B Zvetanov, Sofia, BG;

Lyudmila V Petrova, Sofia, BG;

Vaska A Ognyanova, Sofia, BG;

Milka P Nikolova, Sofia, BG;

Georgi L Tanev, Sofia, BG;

Nedyalka S Ivanova, Sofia, BG;

Assignee:

T P O 'Pharmachim', Sofia, BG;

Attorney:
Primary Examiner:
Assistant Examiner:
Int. Cl.
CPC ...
C07C / ;
U.S. Cl.
CPC ...
560 43 ; 562449 ;
Abstract

This invention relates to biologically active esters of 0(2,6-dichlorophenylamino) phenylacetic acid and a method for their preparation. The inventive esters have the formula ##STR1## wherein R represents a hydroxyl group or the radical ##STR2## and n is an integer from 10-450. The molecular mass of the inventive compounds ranges from 700-30,000, as determined by the vapor pressure method. The inventive compounds may be prepared by reacting 0(2,6-dichlorophenylamino) phenylacetic acid with polyethyleneglycols having the formula HO (CH.sub.2 --CHO.sub.2).sub.n H, where n is as defined above, in the presence of an acid and while heated in an inactive solvent. The inventive compounds exhibit a high antiphlogistic activity, but are much less irritating to the stomach mucosa then the prior art compounds.


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Zabunova, Orhideya. (1987). Esters of o(2,6-dichlorophenylamino) phenylacetic acid (U.S. Patent No. 4704468). U.S. Patent and Trademark Office. https://idiyas.com/patent/badge/4704468

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