The patent badge is an abbreviated version of the USPTO patent document. The patent badge does contain a link to the full patent document.
The patent badge is an abbreviated version of the USPTO patent document. The patent badge covers the following: Patent number, Date patent was issued, Date patent was filed, Title of the patent, Applicant, Inventor, Assignee, Attorney firm, Primary examiner, Assistant examiner, CPCs, and Abstract. The patent badge does contain a link to the full patent document (in Adobe Acrobat format, aka pdf). To download or print any patent click here.
Patent No.:
Date of Patent:
Nov. 03, 1987
Filed:
Nov. 09, 1984
Brian G Main, Sandbach, GB;
Imperial Chemical Industries PLC, London, GB;
Abstract
This invention concerns novel 1,3-dioxan-4-yl-alkenoic and alkanoic acids of formula I wherein Ra is (1-6C)alkyl, halogeno-(1-6C)alkyl, Rb is hydrogen or as Ra, or Ra and Rb together form (2-5C)polymethylene or (2-4C)oxypolymethylene, n is 2, 3 or 4, A is vinylene or ethylene, benzene ring B optionally bears a single substituent and the substituents at positions 4 and 5 of the dioxane ring have trans-relative stereochemistry; together with pharmaceutically acceptable salts, (1-6C)-alkyl esters and (1-6C)alkanesulphonamides thereof. The compounds of formula I are antagonists of thromboxane A.sub.2 and are of value in treating a variety of disease conditions. The invention also provides processes for the manufacture of, and pharmaceutical compostions of, the compounds of formula I.